CBDEXPO MIDWEST

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Hurry and grab your tickets for CBDEXPO MIDWEST 2021!

Powered by Mace Media Group and brought to you by 3CHI, CBD Expo MIDWEST 2021 is the largest CBD event platform to broadcast your products with the community and share your CBD knowledge with the industry. This event will feature hundreds of exhibitors ready to share their innovative products and leading-edge technology.

Choose from thought-provoking panels and exciting activities. Discover the cutting edge of research and medicine. Brush up on regulation and compliance. Fine-tune your marketing skills and improve sales under the guidance of industry experts.

Open to the public, everyone is invited, from entrepreneurs and professionals to curious consumers. MORE THAN 100 VERIFIED STOREFRONT BUYERS ARE SIGNED UP FOR THIS CONFERENCE!

*Smokeable Hemp Flower Not Allowed

Day1 - Panel Room (A)

9:00 am-10:00 am – Reversing The Stigma; or Will it Always be US vs The Plant?

No other medication is as stigmatized as cannabis in the United States. With over a century of prohibition on all forms of cannabis, there is a large sector of healthcare workers that do not have an in depth understanding of the value of cannabis products. Furthermore, the scientists have lost out on most of that 100+ years of potential research. Now that the green wave is sweeping across the country, the science is catching up. Learn how we can collectively reduce the stigma attached to cannabis and take actionable steps to normalize the plant.

10:15 am – 11:00 am – How Much is Right for You: The Science of CBD Dosing

One of the challenges in the emerging CBD market is the lack of robust clinical research that can be used to guide dosing guidelines. This is especially problematic in people with comorbidities or on other medications who would like to explore taking these products medicinally too. Even so, crowdsourcing the anecdotal data has allowed companies to review by developing a functional measure of how much CBD is needed for different conditions. This system, albeit lacking in strong foundations in clinical trials, in some ways is good enough. But when it comes to a product we want to promote as medication, we have a responsibility to produce real data from which to work off of.

11:15 am – 12:00 pm – So, You Think You Can CBD…
(Hemp Derived vs Cannabis Derived CBD and Full Spectrum vs. Broad Spectrum vs. Isolate)

In today’s early stages of the legal hemp marketplace, there are thousands of CBD products available, yet not much in the way of differentiation – at least not knowingly in most cases. All legitimate CBD products contain at least some amount of cannabidiol, but they may also contain (or specifically not contain) other elements, depending on how they’re labeled. In this panel, we examine and specifically define the terms relating to this phenomenon: hemp-derived, cannabis-derived, full-spectrum, broad-spectrum, CBD isolate, and more.

12:00 pm – 12:30 pm – LUNCH BREAK

12:30 pm – 1:15 pm – Get the 411 on Cannabinoid Pharmacology 101

Cannabinoids are wonderful compounds with one very big problem–they are lipophilic, or fat loving. This makes dosing very, very tricky. And why it’s so hard to measure cannabinoid levels in the blood and urine. The pharmacokinetics and pharmacodynamics of cannabinoids are greatly affected by various factors, such as the amount and type of food eaten in a given day, whether other substances, including medications, were taken, and how they were consumed (vape, oil, edible, etc.). For these reasons and more, despite decades of research, the best advice to offer new users remains the “start low, go slow” method, which is as unscientific as it comes. And explains why this topic remains red hot in research.

1:30 pm – 2:15 pm – Creating Novel CBD Formulations and Blends

While scores of people may benefit from CBD isolates, many more have reported respite from their ailments using full-spectrum products that contain many more of the natural molecules native to hemp, like other cannabinoids and terpenes. Still yet, many product manufacturers are looking to design novel formulations that incorporate some of these molecules, without necessarily being considered as “full-spectrum”. These products may contain other minor cannabinoids and terpenes, but the inclusion of these ingredients are done with purposeful intent, such as creating products designed as sleep aids, or for treatment of pain or anxiety. Additionally, blending these formulations with other dietary supplements such as ginseng or melatonin can present an exciting new product line that combine traditional supplements with the surging interest in hemp-derived molecules, thereby presenting the best of both worlds. This panel will help you understand what types of products are currently in demand, and will illustrate how the rapidly evolving CBD industry is changing.

2:30 pm – 3:15 pm – Psychedelics & Cannabinoid Therapeutics: What Does the Future Hold?

Alongside the CBD boom, the functional Mushroom market has experienced a profound amount of growth with certain estimates putting market growth upwards of $35 Billion. Similarly situated to cannabis treatments as both controversial and poorly understood, there remains tremendous potential on the horizon for mycelia like Cordycepin and Psilocybin. As consumers look to herbal treatments for an assortment of ailments and quality of life improves the future of hemp products and mushrooms while regulations take shape the question remains whether or not there is a future for CBD and Mushrooms.

Day1 - Panel Room (B)

10:15 am – 11:00 am – Cannabinoids in Food and Beverage: Market Trends, Innovation, and what the future holds

Food and beverage products from the Cannabis sativa plant have taken off, leading to the constant creation of innovative, new products to fill the cannabinoid-based food and beverage space. Looming in the background of constant growth is the FDA, which has yet to issue a final ruling that would set up an efficient regulatory framework for the industry. Learn about the most cutting-edge cannabinoid food and beverage products and explore what makes them true trend drivers. We will also explore the FDA and what a final ruling could mean for the food and beverage space within the cannabis umbrella.

11:15 am – 12:00 pm – What to Consider When Choosing a White-Labeling Partner

There are a variety of reasons for choosing to white-label your products. White-labeling, also called private-labeling, is the purchasing of a finished product from a company and adding your brand and identity to it. In the hemp and CBD industry, brands choose to white-label oils, isolates, hardware, websites, marketing and advertising content, and more. When choosing your white-labeling partner, shared vision and goals, open communication, transparency and honest reporting, and a good track record of performance are all things you should be looking out for. White-labeling requires strategic thinking and adaptability, and it is paramount that the partner you have in mind can deliver that in a positive way.

12:00 pm – 12:30 pm – LUNCH BREAK

12:30 pm – 1:15 pm – Making the Most Out of the Medicine: Methods for Separating Minor Cannabinoids

CBD might be the well-known cannabinoid regularly extracted from hemp plants, but it is not the only one. Minor cannabinoids, such as CBG and CBC have medicinal properties of their own. While these cannabinoids are typically in much lower concentrations within the plant, they can still be isolated and purified using methods like flash or supercritical fluid chromatography (SFC). The isolation of these cannabinoids, such that adequate purity is achieved, is paramount for better understanding what benefits these cannabinoids impart. In addition, techniques like SFC can help clean up mother liquors to ensure that all of the gold is extracted from the garbage. In this panel, we examine why these minor cannabinoids present such an exciting new development for the industry, how to extract and purify them, and what the future may look like as a result.

1:30 pm – 2:15 pm – Hemp’s Hurdles: Merchant Processing & Business Banking

As regulation surrounding hemp cultivation and processing takes shape there remains tremendous confusion on both the industry and consumer side surrounding payment processing. As the SAFE Banking ACT stalls in the Senate and courts continue to scrutinize 280-E tax filings, support for the financial aspects of CBD sales and production can seem non-existent. Our panel of industry veterans, lawyers, and financial professionals discuss the legal and practical logistics of merchant processing and banking hemp-related monies.

2:30 pm – 3:15 pm – Boost CBD Products with Organic & cGMP Certifications

Wellness consumers in the 21st century are weary of empty promises. Certifications that guarantee exceptional quality are the golden ticket to product recognition and shelf velocity. The two most powerful seals of greatness? Certified organic and certified Good Manufacturing Practices (cGMP). Organic certification indicates that your hemp-derived CBD was not harvested with synthetic pesticides, fertilizers, or solvents. Today’s sharp consumers will know that they are investing in sustainability and the future of the planet. cGMP certification regulates manufacturing practices. It demonstrates that your product is clean, safe, and consistent. CBD and cannabinoid products with these certifications leave the competition in the dust. But the journey to certification is nuanced. The United States Department of Agriculture (USDA) and the Food & Drug Administration (FDA) require that cultivators and manufacturers adhere to specific guidelines and procedures to earn these badges of honor. Fortunately, specialists are available to guide you toward certification — one step at a time.

3:30 pm – 4:15 pm – CBD Industry Association Insider Insight – The Visionaries and their Predications

This panel will offer the opportunity to educate and inform anyone involved within the CBD industry. Current issues and cutting edge developments will be discussed and analyzed by members of the Advisory Board of the CBDIA. Relevant topics that affect anyone in the industry will be highlighted and examined including legal matters, developing science, regulations, and advertising. The CBD industry is rapidly evolving and this panel will offer discussion intended to investigate and evaluate questions and concerns of all things CBD. This opportunity to gain valuable industry insider insight is not to be missed.

Day 1 - Educational Series

10:00 am – 12:30 pm – Use Simple Testing Kits for Cannabinoids From Farm to Pharmacy.

In five hours you will receive an overview of the principles and practices of CBD extraction. With many hands-on demonstrations, you will leave with an understanding of how coffee, hemp, and clothes are similar. You will appreciate the vast number of ways to make eggs, tea, as well as cake and how you can increase your productivity with hemp. Good is not a number. You will gain an understanding of measuring the potency at each stage of sample preparation, extraction, and post-processing; saving you thousands of dollars a week.

02:00 pm – 04:00 pm – Beyond the COA: A workshop on evaluating CBD quality

Dive Deep into the world of cannabinoid quality control with CBD ingredient manufacturer Ryan Shore of Big Sky Scientific. Learn Practical easy to implement tests to find issues that may not show up on your certificate of analysis. This workshop will give an overview of various manufacturing processes and the effect on your final product.

Day1 - Center Stage

10:15 am – 11:00 am – The Gold Standard

The gold standard is the ability to offer your customer the original of what they need. Meaning that they’re not extracting from the cannabis plant, they’re extracting from the industrial farm act bill of 2018, which is legal industrial hemp. That process is more expensive and harder to do. However, the medical market of Thiink Medical Group and Thiink VP is the golden standard. We are compliant and one of the only FDA and COVID-19 compliant manufacturers, if not the only one in the USA. What we want to do is gravitate towards the gold standard as opposed to previous markets which are illegal. I will also talk about hot CBD and how it is extracted from the cannabis plant. People are trying to extract hot CBD and put it into CBD products, which is illegal. Regulations will be coming out in 2022, which will make it a lot harder for people. They will have to have seed to soil and PTCH 1 understanding.

11:15 am – 12:00 pm – A Green Beret’s Advice on Finding Your New Frontier in Hemp and Cannabis

The hemp and cannabis industries are still new contrary to what most believe here in the states and abroad. There are states and countries that still do not have a program in place. Countries and states, for that matter, still exist that demonize the plant even though you can walk into a store in a legal state and get anything that your heart desires. The hemp industry here in North America is still lacking vital logistics to make USA hemp a feasible option for farmers and the “Made in USA” consumers. The international hemp market has a head start on our country and has had such start for a considerable amount of time. Countries and brands are claiming their market share but these industries will be growing before our very eyes and offering wild new opportunities for the foreseeable future. It is awesome to see this plant take it’s place back in our lives, now matter how you use it or consume it.

02:15 pm – 03:00 pm – CBD LABELING AND PACKAGING — 16 THINGS BRANDS NEED TO KNOW

The CBD industry finds itself in a tricky place right now.

Why? Largely because of weird timing. The people’s interest (and confidence!) in CBD have far outpaced their actual knowledge of CBD.

This interest has outpaced the government’s ability to regulate CBD, too. A lack of strict CBD labeling requirements has led to all sorts of mislabeled CBD products. Some products are accidentally mislabeled (maybe they don’t indicate their THC content)…other products intentionally push the envelope and try to stand out by making wild health claims. Either way, mislabeled products are running rampant, and that’s led to a whole lot of lawsuits.

03:15 pm – 04:00 pm – From Reefer Madness to CBD Utopia?: Challenges and Opportunities in Retail & Wholesale

It all starts with a dream, or hope, or a mission, or a purpose, or a calling. The dream of entering the CBD industry with plans of striking it big in the Green Rush. But how will you bring it to life? What are the realities of the industry? The task of getting your dispensary up and running or getting your distribution channels flowing as a wholesaler can be an extremely complicated and overwhelming process, but not impossible. You need a plan and industry insight. That is where this session can help. This educational session will focus on some of the significant issues CBD brick-and-mortar dispensaries and wholesalers must maneuver daily. This session will offer some actional tips you can use right now to help you navigate the uncertain market that is CBD.

Day2 - Panel Room (A)

9:00 am-10:00 am – Translation of Bench Side Cannabinoid research into Precision Based Therapeutic Care

Dr. Annabelle is a cell and developmental biologist from Vanderbilt University. While her background is in Neuroscience and Cardio-Oncology, Dr. Annabelle opened her eyes to cannabis in developing a treatment for her baby son after he had a 38% brain resection. Successful in alternative implementation of cannabis on her child, Dr. Annabelle is interested in the cannabinoid specific mechanisms that can combat disease at the precision based level. As a cell biologist, Dr. Annabelle introduces the importance of sorting through the variability and defining the synergy of cannabis molecules in cellular homeostasis.

10:15 am – 11:00 am – Delta 8, CBC, CBN, CBG & More Minors

The Others: Your eyes don’t deceive you. This is a CBD Expo, but there are many more therapeutic molecules in hemp, including so-called minor cannabinoids like CBC, CBN, and CBG as well as moieties that are still to be fully appreciated. Our experts assembled on this panel are hoping to familiarize consumers with the diversity of plant chemicals that cannabis has to offer. From how they are extracted, isolated, and synthesized to how they can be utilized in product formulation, this panel will aim to introduce these novel compounds and guide listeners to where they can learn and experience more. Understanding developments surrounding products, science, and culture as well as cannabis and hemp as CBD becomes increasingly mainstream is important to understanding how to unlock the full potential of the plant and understand how the industry is developing into the new decade.

11:15 am – 12:00 pm – The Cutting Edge of Cannabinoid Science

Science has transformed the world of cannabinoids. CBD was once a relatively obscure, banned substance. But scientific research landed this compound in the hands of physicians, engineers, lawmakers, and consumers. In fact, research fuels innovation. Designers rely on emerging scientific evidence to develop cannabinoid products that meet the needs of an evolving market. Where is the science of CBD today? The past year’s breakthroughs in CBD research include medication interactions, epilepsy, neuroscience, dermatological applications, mental health disorders, addiction/relapse, and biochemistry. This council of established scientists will push your company to the cutting edge of chemical/medical advancement in the field. Critics often point out that CBD claims are ahead of science. But knowledge is power.

12:00 pm – 12:30 pm – LUNCH BREAK

12:30 pm – 1:15 pm – Cannagriculture: Scaling Cannabinoid Cultivation

As state legislative barriers to hemp cultivation continue to fall in succession, hemp farming has officially, rapidly, and monumentally become a part of the agriculture industry. Hemp farmers often solicit techniques that harmonize with the larger picture of sustainable agriculture, where soil and crops remain healthy beyond annual cultivation cycles, and what is added to the earth does not taint it. This panel discusses the increasing importance of organic hemp farming.

1:30 pm – 2:15 pm – Coming to your Senses: Terpenes + CBD

For some time, terpenes were considered waste molecules leftover after extracting CBD. Those times were short-lived, however, since there is an abundant wealth of scientific literature demonstrating the medicinal merit of terpenes like beta-caryophyllene, linalool, bisabolol, nerolidol, and more. For example, nerolidol and linalool are useful in treating anxiety, whereas beta-caryophyllene is useful in relieving pain. While some patients may benefit from more one-dimensional CBD products like isolate, the terpenes native to the plant can help augment the benefits of the extracted cannabinoid(s). This panel will discuss the importance of terpenes, and how adding these precious little molecules back into CBD oils can differentiate a product to have a defined medical purpose.

Day2 - Panel Room (B)

10:15 am – 11:00 am – Food & Drug Compliance And Federal Enforcement

Fighting the authorities can be a struggle. Although long-held rules and regulations on CBD and other cannabinoids are rapidly changing, it still pays to pick your battles and know your rights. One wrong move in your CBD companies manufacturing process or production line can have the authorities breathing down your back, imposing huge fines at best and shutting your business down altogether in a worst-case scenario. Don’t let this happen to you. Understand “The Man” and why it pays to follow the rules with this panel aimed at taking the crosshairs off of your business with a look at the requirements, processes, and protocols to stay in good standing with the FDA and other federal enforcement.

11:15 am – 12:00 pm – The Art of CBD and Cannabinoid Potency Testing

With legal regulations and consumer awareness ever on the rise, precise testing of CBD and other cannabinoids is paramount to ongoing success. This panel will dive into the best methods and practices to measure cannabinoid potency levels from any CBD or cannabis derived product. Accuracy is key for any grower or producer of hemp for CBD to comply with state or federal regulations. Exact cannabinoid potencies are also becoming the standard in which an informed public makes their purchasing decisions. We will look at how to achieve accurate potency tests by examining the techniques and equipment needed to do so while highlighting the growing importance of cannabinoid testing to differentiate products in a competitive market. The Art of CBD and Cannabinoid Potency Testing panel will offer expert opinion and analyses from experienced producers, business owners, and researchers in the CBD and cannabis industries.

12:00 pm – 12:30 pm – LUNCH BREAK

12:30 pm – 1:15 pm – Claims and descriptions: A Legal Opinion on What You Can and Cannot Say

With various levels of legalization taking place nationwide, ensuring that your messaging falls within legal guidelines are crucial. From packaging and advertising content to marketing initiatives and sales collateral, there are a number of pitfalls CBD companies are liable to make when discussing the plant and its products. One incorrectly used word could potentially result in fines, shutdowns, and more. Here, we give you the ins and outs of precisely what can and cannot be said in your messaging, packaging, and branding. Stop having to worry about whether or not you are in compliance by listening to what the experts have to say.

1:30 pm – 2:15 pm – 2021 INSIGHT: CBD Regulations in the Midwest

As we move into the first calendar year, the DEA no longer considers Hemp to be a controlled substance, the regulation of the hemp industry finally moves towards a place of clarity. As banking and production rules and taking shape on a federal level, individual states move to craft plans that will fit their particular localities. Understanding how states operate is crucial to running a compliant and successful national brand. As a legal medical marijuana state with a widespread hemp industry, Midwest regulators are crafting their own way. Between recent decisions to functionally decriminalize cannabis, alongside executive orders banning smokable hemp and creating a registry for CBD sellers there is a lot to know about operating in the Midwest.

2:30 pm – 3:15 pm – How to Approach CBD Marketing For Entrepreneurs and Start-Ups: Q&A

So you started a cannabidiol business and are looking to scale up but not sure how? The key to a successful company is good marketing–and CBD is no exception. But even for seasoned pros, the transition to CBD may be a bit bumpy. The blossoming industry is going through some growing pains as regulators work to come up with guidelines. To avoid chaos, consider developing marketing messages that are based on the science of the product and reflect the needs of the consumer/patient audience. A strategic integrated approach targeted to key stakeholders with messages that carefully balance product/service benefits is a good start to kick off long-lasting relationships with patients and consumers.

Day2 - Educational Series

10:00 am – 10:45 am – TBA

11:00am – 11:45 am – Solubility and Kinetic Aspects of Processing/Extraction, Product Formulation, and Packaging in Cannabis-Hemp Technology

The solubility properties of cannabinoids, terpenes along with their co-extractives is seminal to the design and optimization of extraction protocols, end product formulation; and also a major factor in the choice of materials in which cannabis hemp products are packaged. In this presentation we shall show that there is a paucity of solubility data for cannabis/hemp constituents in extraction solvents – a condition that can be partially solved by utilizing theory and semi-empirical correlations. Data mining for solubility data related to extraction – and post extraction processing, such as “winterization”, anti-solvent based precipitation- will be noted with select examples. We have found that the Hansen Solubility Parameter (HSP) can be used to explain the salient features of both sub- and super-critical extractions (butane and CO2) as well extraction/fractionation using conventional liquid-state solvents. The options for experimental determining HSPs as well as their “theoretical” calculation will be presented and correlated with well-known thermodynamic concepts such as activity coefficients, chi-interaction parameters, and solute-solvent phase diagrams. The importance of cannabinoid, terpene, and associated compound solubility’s can be extended into the formulation of stable end-products (or not!) including alcoholic tinctures, various infused matrices (both nonpolar oily concoctions and polar polymeric amorphous and glassy substrates) called canna butters, , gummies, etc. A special note will be made of “false” solubility of cannabinoids and terpenes in various aqueous media, and the stability of these liquid concoctions. Finally a connection will be made between product formulations and the choice of packaging for “flower”, vape concentrates and particularly the use of polymeric materials such as poly-olefins, PET, used in vials, lids, and encapsulates. In packaging and sustained delivery systems (ex. – transdermal patches), as well as in extractions, the permeation or flux of cannabis/terpene constituents is proportional to the solute’s solubility (S) times its diffusion coefficient (D) in solvents as well as the aforementioned polymeric materials. Such packaging materials must be chosen wisely in order to avoid loss of cannabinoids/terpenes into the packaging substrate, or vice versa the absorption of adjuvants found in polymeric materials into the cannabis/hemp products. This particularly becomes acute with aqueous-based infusions of cannabis constituents which can result in their loss into the packaging matrix, i.e. flavor scalping in the case of terpene losses.

12:00 pm – 12:45 pm – Women’s Health and Phytocannabinoids

This lecture will examine and highlight the exciting potential that this growing field of study is demonstrating. Taught by Dr. Becky Kaufman Lynn, a board certified gynecologist and sexual counselor who specializes in women’s sexual health, gynecologic care, and menopause, this course offers expert insight into a number of women’s health concerns and how phytocannabinoids can be used to assist. Participants will gain practical knowledge as well as look into future applications while positioning themselves as specialists in a growing and in-demand niche within the health, wellness, and cannabinoid industries.

2:15 pm – 03:00 pm – The Controlled Substance Registration License – Is It Right For Your Company?

By definition, any plant or hemp-derived product containing over 0.30% THC is considered marijuana, a Schedule One Controlled Substance. This places lab owners, CBD formulators and processors into a very worrisome position, since initial CBD crude and distillate from legal hemp has THC levels of 2-3% upon extraction. These materials are considered a liquid form of marijuana, by the USDA and DEA’s own definitions. Neither agency has made an attempt to clarify their position on the matter with an amendment of their definition of “Hemp Product,”which means every lab owner out there runs the risk of being fined, shut down, and even prosecuted. The solution? Obtain your Controlled Substance Registration/License and protect your business (and yourself) from a potential catastrophe. This presentation is your introduction to the hemp lab CSR. I laid the groundwork for it in Indiana in 2020 and am currently the only hemp operator in the state with the license. Come find out if it’s right for you!

Day2 - Center Stage

10:15 am – 11:00 am – Massage Therapy, MedSpas & CBD

Join JulieB, Nationally Certified Massage Therapy Educator, Award Winning MedSpa Owner, & CBD Massage Oil creator to see how CBD can help brick and mortar wellness businesses grow. Watch and learn how to repeat a proven method for incorporating CBD into a menu of services. Enjoy a demo of different touch therapies that can incorporate CBD, and think about how they can apply to you or your sales process. See how you can help local massage therapy clinics, chiropractic offices, and other wellness professionals add to their client results and bottom lines with a wide range of CBD based services.

11:15 am – 12:00 pm – How to Survive & Thrive in the Covid 19 Era

Colby Watkins is a former award-winning software sales executive and networking guru who transitioned into the hemp space 4 years ago. It was then that he started the CBD & Cannabis Professional business network, which has since blossomed into the largest group of its kind on LinkedIn with over 24,000 members. He is also the Co-Founder of Wherezhemp, an online B2B lead generation and marketing platform for the Hemp and Cannabis industry. Watch and learn as Colby talks about how business challenges have historically been handled in the cannabis and hemp world, and what are the best practices for overcoming business challenges in the Post Covid-19 era.

01:15 pm – 02:00 pm – Isolating Pure Cannabinoids with Chromatography

Various forms of chromatography coupled with adsorbents have been applied in the cannabis/hemp technology platforms both on an analytical as well as a processing scale. This presentation will emphasize the use of the various modes of chromatography on the process scale for the further purification of extracts and isolation of pure cannabinoids and terpene-enriched fractions, although synchrony and non-synchrony with analytical methods will be cited. Examples of frontal, displacement, and elution modes of chromatography as applied to the purification of the cannabinoid and terpene compounds found in cannabis or hemp – which will include the more simple adsorbent-based isolation of desired components as well as the more complex procedures employing countercurrent partition chromatography (CPC), simulated moving bed techniques (SMB), as well as columnar elution chromatography. These advantages/disadvantages of these techniques will be discussed along with the use of solid phase extraction (SPE) sorbent approaches, matrix solid phase dispersion (MSPD), size exclusion chromatography (SEC) media and molecular-imprinted polymers to fractionate both wanted and unwanted components from cannabis/hemp extracts. Useful correlations will be provided based on analytical-scale separation of cannabinoids and COA analysis with solute (cannabinoid) properties such retention capacity factors (k’), solubility parameters (δ), and breakthrough volumes (BTVs). A particular emphasis will be placed on the role of sub- and super-critical fluid chromatography (SFC) as a “green” technology to complement SFE using (CO2), based on the presenter’s 55 years of experience in the field. The combination of SFC with SFE provides a viable alternative to the use of organic solvent media in chromatography-based purifications often utilized in CPC and countercurrent chromatography (CCC). Parallels will be drawn between SFC use in food industry that can also be utilized in the separating the components found in cannabis or hemp concentrates. Finally some examples pertinent in the cannabis and hemp field, such as THC-removal, terpene trapping, and the removal of lipid- or wax-co-extractives along with unwanted compounds having chromaphoric (color) properties will be described.

02:15 pm – 03:00 pm – How to Identify Effective Cannabinoids

The real effectiveness of cannabis/hemp extracts is crucial in the formulation of final CBD/hemp products. Although chemical analyses (COAs) show the amount/potency of CBD, cannabinoids, and/or terpenes in hemp extracts, these COAs are not proof of effectiveness. Midwest Hemp Testing Services/DSTest Laboratories are using biological assays to evaluate and validate effectiveness of CBD/hemp extracts. Our data demonstrates anti-inflammatory activity of specific cannabinoids, hemp extracts, and terpenes. Moreover, we found synergistic effects of many combinations of cannabinoids and terpenes in the suppression of inflammation in immune cells. Our results show that in addition to the cannabinoids/CBD potency (concentrations), the real effectiveness (for example anti-inflammatory activity) should be tested. Hemp extracts, including CBD isolate, full, and/or broad spectrums have different CBD/cannabinoids amounts and ratios and therefore they have different effectiveness. This cell-based testing is crucial for the development and validation of highly effective CBD/hemp products. Midwest Hemp Testing Services and DS Test Laboratories is here to help you.